Clinical Trials & Research

In a recent study, researchers tested different types of antibiotics as a potential endometriosis treatment. Endometriosis is a chronic condition that can lead to pelvic and lower abdominal pain and infertility. About 10% of women between 25 and 40 years old have endometriosis. This condition can cause a significant reduction in quality of life. Endometriosis
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A recent study suggests that older people who regularly use sleeping pills may end up needing more blood pressure medications to control their blood pressure.   High blood pressure is a common condition among older aged people. Fortunately, blood pressure medications can reduce blood pressure and therefore reduce the cardiovascular risks associated with the condition.
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A new study in the Journal of Experimental Medicine investigated the molecular factors behind the gender disparity in liver cancer development.   According to a 2108 study based on data from the International Agency for Research on Cancer, liver cancer is the fourth most lethal form of cancer worldwide. Hepatocellular carcinoma (HCC), the most common
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Researchers analyzed evidence from previous studies to determine the most effective approaches for treating urinary incontinence in women.   Urinary incontinence is the involuntary loss of bladder control causing urine leakage. There are two main types: stress incontinence and urgency incontinence. Stress incontinence occurs after coughing, sneezing or physical exertion, and urgency incontinence occurs when
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Physicians from McMaster University in Canada recently published a list of facts about penicillin allergy the public may not know. The document is published in the Canadian Medical Association Journal (CMAJ).   Almost a century has passed since the discovery of the first antibiotic. Nowadays, antibiotics are among the most prescribed drugs. Among them, penicillins
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In Southwestern Ontario, researchers studied if environmental factors are associated with adverse birth outcomes such as low birth weight and preterm birth.   Adverse birth outcomes can lead to disease and mortality. Within developing countries, the percentage of babies born with low birth weight is 16.5%, and in developed countries, that number is 7%. There
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Short-term use of the weight-loss drug phentermine is approved by the US FDA. Researchers conducted an analysis to determine if its long-term use is also safe and effective.   Lifestyle changes can help people with obesity lose weight. These interventions result in only 5-10% weight loss after six months. Also, about one-third of individuals will
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A recent study published in JAMA Internal Medicine analyzed how consistent drug safety warnings are among the world’s leading drug regulators.   Health products, ranging from pharmaceutical drugs to natural health products, play an important role in Canada’s healthcare system. Currently, more than 22,000 human drug products available on the Canadian market. Health Canada plays
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A recent study examined important factors in preventing suicide among middle-aged men to develop a potential multimedia program for individuals visiting their primary doctor’s office.   Discussions regarding common causes of death often bring up thoughts of serious medical conditions, such as cancer and cardiovascular diseases. Yet, one cause, perhaps all-too-often overlooked in this discussion
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В недавнем исследовании ученые из Финляндии изучили, почему посещение сауны полезно для здоровья   На протяжении тысячелетий жители Финляндии посещают сауну, чтобы расслабиться и, как считается, улучшить здоровье. Однако научные данные о пользе сауны были неоднозначными. Учитывая пробел в этих знаниях, финские ученые провели обширный анализ публикаций, чтобы определить, существует ли связь между посещением сауны
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There is a need for new types of cholesterol treatment. A recent study investigated whether a drug called bempedoic could work alongside other cholesterol-lowering drugs.   LDL cholesterol, sometimes referred to as “bad cholesterol”, can build up in blood vessels. This is an important cause of cardiovascular disease since blockages of blood vessels can lead
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A recent study published in Frontiers in Psychiatry determined the overall health effects of smartphone use in Australia.   The past decade has shown a dramatic increase in the use of smartphones. It is estimated that 2.5 billion people use smartphones worldwide. In 2017, 64% of the United States population owned smartphones. Currently, in Australia, 88%
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A large clinical trial funded by Astra-Zeneca compared the safety between two blood thinners – clopidogrel and ticagrelor. Heart attacks are the second leading cause of death in Canada. The development and trapping of blood clots in vessels that supply the heart with blood can cause heart attacks. In many cases, these clots can originate from a
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Researchers compared complications of atrial fibrillation between treatments with catheter ablation and drug therapy.   Atrial fibrillation is a serious condition where the heart does not make regular beats. It affects 2.7 million Americans and can cause extreme tiredness and shortness of breath in some patients. For many years, atrial fibrillation was treated with drug
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A new study investigated the association between vascular risk factors such as smoking, high blood pressure, diabetes, and BMI, and the structure of the brain.   Non-pathological brain ageing is a brain condition more prevalent than dementia. It can cause functional consequences that seriously impede that independence and quality of life of the elderly. Neurovascular
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An increasing number of deaths caused by opioid overdose has generated a need for new painkillers. A recent study conducted in rats investigated a new painkiller developed using nanoparticle technology.   In 2017, about 17 Canadians per day were hospitalized due to opioid overdoses. In the United States, over 115 people die from opioid overdose
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A recent article published in the Canadian Medical Association Journal assessed the maternal risks associated with infertility treatments. Every year, up to 4% of births in Canada result from the use of infertility treatments. Treatments such as in vitro fertilization and ovulation induction provide couples who have difficulty getting pregnant with the opportunity to have
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Reading Time: 3 minutes Researchers recently examined a patient case who developed chest pain and obstructed blood flow to the heart after consuming a marijuana lollipop.   The use of marijuana carries risk and side effects, just like all other medications. In a recent case, inappropriate dosing and consumption of marijuana by an older patient
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Reading Time: 2 minutes Researchers from the University of Adelaide determined the effect of previous orthodontic treatments on long-term oral health and dental caries. Maintaining a daily oral health routine is a vital part of dental health. Aside from the basics of brushing and flossing at home, attending regular dentist appointments are also important for
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Reading Time: 3 minutes A recent study sought to evaluate how often emergency departments are discharging patients with prescriptions that can cause drug interactions with their home medications. Approximately 25% of patients in the community experience an adverse drug reaction, of which 39% are preventable. Most of these preventable adverse drug reactions are from drug-drug
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