Month: August 2017

Researchers find that proactively removing more than 24 lymph nodes can help the long term outcome of patients with Oral Cavity Squamous Cell Carcinoma. Surgical nodal dissection or excision involves removing lymph nodes affected by cancer and simultaneously determining the stage of cancer.Benefits of such measures include staging cancer and limiting the spread of cancer
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Scientists compared three anti-epileptic drugs including one branded Lamotrigine and two lamotrigine-generic drugs and found them to be bioequivalent. Now we know: branded and generic drugs can be substituted with confidence. It is estimated that nearly 80% prescriptions filled in the US are for generic drugs. The US Food and Drug Administration (FDA) requires that
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Scientists at the Center for Injury Research and Prevention at the Children’s Hospital of Philadelphia asked the question; “what is the association between attention-deficit/ hyperactivity disorder (ADHD) and car crashes involving young adult drivers, and does this vary by sex, licensing age, and/or being prescribed ADHD medication?” Car crashes are the leading cause of death
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In a 2017 study, researchers explored the risks and benefits of levothyroxine for subclinical hypothyroidism treatment in older adults. The findings suggest levothyroxine does not improve hypothyroidism symptoms. Hypothyroidism – underproduction of the thyroid hormone thyroxine and compensatory overproduction of the pituitary hormone which promotes its release, thyroid-stimulating hormone (TSH) –can have profound effects on
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A small-molecule drug inhibitor called vismodegib successfully treated a dire case of infiltrative basal cell carcinoma. According to the authors, this case qualifies as a first to report a complete remission for this subset of skin cancer. Basal cell carcinoma (BCC) is one of the most common types of skin cancer. For patients with locally
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A meta-analysis combining results across studies assessed outcomes of tight versus standard glucose management on the prevention of onset and progression of end-stage kidney disease (ESKD) in diabetic patients. Study results suggest that diabetic patients who were under stringent glucose control have a comparable risk of kidney failure to those under standard glucose management. Diabetes
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Chronic kidney disease is both a cause and consequence of hypertension. In patients with both conditions, accurate evaluation and a tailored treatment program are essential for successful hypertension management. Blood circulates through the body at a certain pressure within the arteries. This pressure changes depending on activity levels– elevating during exercise, to increase the blood
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Stress urinary incontinence, a condition in which individuals experience incontinence during physical exertion, could affect up to half of older adults and may lead to a reduction in quality of life. In a randomized clinical trial, Liu and colleagues show that electroacupuncture may be an effective treatment for stress urinary incontinence. Stress urinary incontinence, or
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The National Audit Office (NAO) published a report on July 27th regarding the inappropriate handling of unprocessed clinical correspondence, leading to a backlog, by the NHS Shared Business Services (NHS SBS). The National Audit Office (NAO) in the United Kingdom published a report on July 27th regarding the inappropriate handling of unprocessed clinical correspondence by
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Cardiovascular diseases are currently the leading cause of mortality worldwide. A group of researchers led by Jeffrey Cohen introduced a new method of preventing heart attacks using photosynthetic bacteria. According to the World Health Organization, cardiovascular diseases are the leading cause of mortality worldwide. Different strategies are being studied to improve
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A recent study published in JAMA Psychiatry found that some adolescents, especially males, who lived in disadvantaged neighbourhoods showed abnormal changes in brain structure from early to late adolescence. Positive parenting may protect against changes in brain structure, counteracting the biological and functional consequences associated with disadvantage. The biological, psychological, and social consequences of socioeconomic
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Diabetic foot ulcers are one of the most common complications affecting diabetic patients. A recent review article outlines preventative measures that can decrease the odds of developing foot ulcers. Diabetic foot ulcers, especially on the bottom of the foot, are a common problem in diabetics. Up to 26.1 million diabetic patients worldwide are estimated to
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PET scanning revealed elevated translocator protein in several regions comprising the neurocircuitry of Obsessive Compulsive Disorder (OCD), indicating a pathogenic role for microglia in the neuropathogenesis of OCD. Though several Hollywood stars have been diagnosed with OCD, no one is better remembered for suffering from this debilitating condition than Howard Hughes of ‘The Aviator’. Characterized
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Deep brain stimulation (DBS) of the thalamus is a well-known treatment for tremor related to Parkinson’s disease, but the research surrounding its efficacy with multiple sclerosis tremors remains inconclusive. DBS of two thalamic nuclei was found to significantly decrease tremor severity over the course of 6 months in individuals with multiple sclerosis tremors. Multiple sclerosis
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A new study validates the use of minimally invasive autopsies (MIAs) to accurately determine the cause of death in stillbirths and neonatal deaths. Since MIAs are less invasive, simpler, and more feasible, they could be an excellent tool to guide the development of preventative strategies to improve child survival in low-income, high-burden communities. Each year,
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Reducing maternal mortality rates has been a long-term goal of public health officials. In the past, the majority of research has focused on infant mortality and its relation to the mother’s age (maternal age), leaving the connection between maternal mortality rates and maternal age understudied. Recent research indicates that maternal mortality rates increase significantly after
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Metabolic syndrome is a group of risk factors that increase the likelihood of developing heart disease and diabetes. Previous studies have identified aerobic and resistance exercise as protective factors that potentially reduce the risk of metabolic syndrome. A study on middle-aged healthy adults found that both aerobic and resistance exercises decrease the risk of developing
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Chikungunya virus is a mosquito-borne virus for which recent outbreaks in human populations have drawn a lot of interest from the scientific community. Luckily, a group of investigators recently reported the development of a monoclonal antibody with therapeutic potential in a macaque monkey model of the disease. Chikungunya virus (CHIKV) can be transmitted to humans
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Lifestyle interventions were effective in reducing the rate of diagnosis of diabetes in prediabetic adults when compared with standard treatment with medication. Researchers also noted improved control of blood sugar, improved exercise capacity, and increased weight loss with lifestyle adaptations. Nevertheless, issues with adherence to lifestyle changes caused deterioration in long-term health improvements. George Kerrison,
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